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Analytical study of robustness of a negative feedback oscillator by multiparameter sensitivity

BACKGROUND: One of the distinctive features of biological oscillators such as circadian clocks and cell cycles is robustness which is the ability to resume reliable operation in the face of different types of perturbations. In the previous study, we proposed multiparameter sensitivity (MPS) as an in...

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Detalles Bibliográficos
Autores principales: Maeda, Kazuhiro, Kurata, Hiroyuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4305980/
https://www.ncbi.nlm.nih.gov/pubmed/25605374
http://dx.doi.org/10.1186/1752-0509-8-S5-S1