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Modeling DNA affinity landscape through two-round support vector regression with weighted degree kernels

BACKGROUND: A quantitative understanding of interactions between transcription factors (TFs) and their DNA binding sites is key to the rational design of gene regulatory networks. Recent advances in high-throughput technologies have enabled high-resolution measurements of protein-DNA binding affinit...

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Detalles Bibliográficos
Autores principales: Wang, Xiaolei, Kuwahara, Hiroyuki, Gao, Xin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4305984/
https://www.ncbi.nlm.nih.gov/pubmed/25605483
http://dx.doi.org/10.1186/1752-0509-8-S5-S5