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RAD51 and MRE11 dependent reassembly of uncoupled CMG helicase complex at collapsed replication forks
In higher eukaryotes the dynamics of replisome components during fork collapse and restart are poorly understood. Here, we reconstituted replication fork collapse and restart by inducing single-strand DNA (ssDNA) lesions that create a double-strand break (DSB) in one of the replicated sister chromat...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4306020/ https://www.ncbi.nlm.nih.gov/pubmed/22139015 http://dx.doi.org/10.1038/nsmb.2177 |