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Acute promyelocytic leukemia with JAK2 V617F and severe differentiation syndrome
Myeloproliferative neoplasms transformed into AML usually have a poor prognosis. We report a case of essential thrombocythemia with myelofibrosis that transformed into acute promyelocytic leukemia (APL) with both the t(15;17) translocation as well as the JAK2 V617F mutation. Clinically, this case wa...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4306096/ https://www.ncbi.nlm.nih.gov/pubmed/25628989 http://dx.doi.org/10.1016/j.lrr.2014.12.003 |