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Acute promyelocytic leukemia with JAK2 V617F and severe differentiation syndrome

Myeloproliferative neoplasms transformed into AML usually have a poor prognosis. We report a case of essential thrombocythemia with myelofibrosis that transformed into acute promyelocytic leukemia (APL) with both the t(15;17) translocation as well as the JAK2 V617F mutation. Clinically, this case wa...

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Detalles Bibliográficos
Autores principales: Braun, Theodore P., Maxson, Julia E., Agarwal, Anupriya, Dunlap, Jennifer, Spurgeon, Stephen E., Traer, Elie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4306096/
https://www.ncbi.nlm.nih.gov/pubmed/25628989
http://dx.doi.org/10.1016/j.lrr.2014.12.003