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DNA methyltransferase inhibition accelerates the immunomodulation and migration of human mesenchymal stem cells

DNA methyltransferase (DNMT) inhibitors regulate target gene expression through epigenetic modifications, and these compounds have primarily been studied for cancer therapy or reprogramming. However, the effect of DNMT inhibitors on the immunomodulatory capacity of human mesenchymal stem cells (hMSC...

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Detalles Bibliográficos
Autores principales: Lee, Seunghee, Kim, Hyung-Sik, Roh, Kyoung-Hwan, Lee, Byung-Chul, Shin, Tae-Hoon, Yoo, Ju-Mi, Kim, Yu-Lee, Yu, Kyung-Rok, Kang, Kyung-Sun, Seo, Kwang-Won
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4306122/
https://www.ncbi.nlm.nih.gov/pubmed/25620445
http://dx.doi.org/10.1038/srep08020