ZnT2 is a critical mediator of lysosomal-mediated cell death during early mammary gland involution

Mammary gland involution is the most dramatic example of physiological cell death. It occurs through an initial phase of lysosomal-mediated cell death (LCD) followed by mitochondrial-mediated apoptosis. Zinc (Zn) activates both LCD and apoptosis in vitro. The Zn transporter ZnT2 imports Zn into vesi...

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Detalles Bibliográficos
Autores principales: Hennigar, Stephen R., Seo, Young Ah, Sharma, Supriya, Soybel, David I., Kelleher, Shannon L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4306139/
https://www.ncbi.nlm.nih.gov/pubmed/25620235
http://dx.doi.org/10.1038/srep08033

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4306139/
https://www.ncbi.nlm.nih.gov/pubmed/25620235
http://dx.doi.org/10.1038/srep08033

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