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Functional Characterisation of a TRPM2 orthologue from the sea anemone Nematostella vectensis in human cells
The human non-selective cation channel TRPM2 represents a mediator of apoptosis triggered by oxidative stress. The principal agonist ADP-ribose binds to the cytosolic domain of TRPM2, which is homologous to the human ADP-ribose pyrophosphatase NUDT9. To further elucidate the structure-function relat...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Nature Publishing Group
2015
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4306143/ https://www.ncbi.nlm.nih.gov/pubmed/25620041 http://dx.doi.org/10.1038/srep08032 |