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Functional Characterisation of a TRPM2 orthologue from the sea anemone Nematostella vectensis in human cells

The human non-selective cation channel TRPM2 represents a mediator of apoptosis triggered by oxidative stress. The principal agonist ADP-ribose binds to the cytosolic domain of TRPM2, which is homologous to the human ADP-ribose pyrophosphatase NUDT9. To further elucidate the structure-function relat...

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Detalles Bibliográficos
Autores principales:	Kühn, Frank J. P., Kühn, Cornelia, Lückhoff, Andreas
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2015
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4306143/ https://www.ncbi.nlm.nih.gov/pubmed/25620041 http://dx.doi.org/10.1038/srep08032

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