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Rad51 protects nascent DNA from Mre11 dependent degradation and promotes continuous DNA synthesis
The role of Rad51 in an unperturbed cell cycle has been difficult to dissect from its DNA repair function. Here, using electron microscopy (EM) to visualize replication intermediates (RIs) assembled in Xenopus laevis egg extract we show that Rad51 is required to prevent the accumulation of ssDNA gap...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2010
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4306207/ https://www.ncbi.nlm.nih.gov/pubmed/20935632 http://dx.doi.org/10.1038/nsmb.1927 |