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Protein-bound polysaccharide K suppresses tumor fibrosis in gastric cancer by inhibiting the TGF-β signaling pathway

Peritoneal carcinomatosis (PC) is the most frequent metastatic pattern of gastric cancer and its prognosis is extremely poor. PC is characterized by rich fibrosis and the development of obstructive disorders such as ileus, jaundice and hydronephrosis. Epithelial-mesenchymal transition (EMT) is one o...

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Detalles Bibliográficos
Autores principales: SHINBO, TOSHIFUMI, FUSHIDA, SACHIO, TSUKADA, TOMOYA, HARADA, SHINICHI, KINOSHITA, JUN, OYAMA, KATSUNOBU, OKAMOTO, KOICHI, NINOMIYA, ITASU, TAKAMURA, HIROYUKI, KITAGAWA, HIROHISA, FUJIMURA, TAKESHI, YASHIRO, MASAKAZU, HIRAKAWA, KOUSEI, OHTA, TETSUO
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4306268/
https://www.ncbi.nlm.nih.gov/pubmed/25435013
http://dx.doi.org/10.3892/or.2014.3636