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Unraveling the Interaction between FcRn and Albumin: Opportunities for Design of Albumin-Based Therapeutics
The neonatal Fc receptor (FcRn) was first found to be responsible for transporting antibodies of the immunoglobulin G (IgG) class from the mother to the fetus or neonate as well as for protecting IgG from intracellular catabolism. However, it has now become apparent that the same receptor also binds...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4306297/ https://www.ncbi.nlm.nih.gov/pubmed/25674083 http://dx.doi.org/10.3389/fimmu.2014.00682 |