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Differential neuroprotective potential of CRMP2 peptide aptamers conjugated to cationic, hydrophobic, and amphipathic cell penetrating peptides

The microtubule-associated axonal specification collapsin response mediator protein 2 (CRMP2) is a novel target for neuroprotection. A CRMP2 peptide (TAT-CBD3) conjugated to the HIV transactivator of transcription (TAT) protein’s cationic cell penetrating peptide (CPP) motif protected neurons in the...

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Detalles Bibliográficos
Autores principales: Moutal, Aubin, François-Moutal, Liberty, Brittain, Joel M., Khanna, May, Khanna, Rajesh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4306314/
https://www.ncbi.nlm.nih.gov/pubmed/25674050
http://dx.doi.org/10.3389/fncel.2014.00471