Killing of Staphylococci by θ-Defensins Involves Membrane Impairment and Activation of Autolytic Enzymes

θ-Defensins are cyclic antimicrobial peptides expressed in leukocytes of Old world monkeys. To get insight into their antibacterial mode of action, we studied the activity of RTDs (rhesus macaque θ-defensins) against staphylococci. We found that in contrast to other defensins, RTDs do not interfere...

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Detalles Bibliográficos
Autores principales: Wilmes, Miriam, Stockem, Marina, Bierbaum, Gabriele, Schlag, Martin, Götz, Friedrich, Tran, Dat Q., Schaal, Justin B., Ouellette, André J., Selsted, Michael E., Sahl, Hans-Georg
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4306331/
https://www.ncbi.nlm.nih.gov/pubmed/25632351
http://dx.doi.org/10.3390/antibiotics3040617

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4306331/
https://www.ncbi.nlm.nih.gov/pubmed/25632351
http://dx.doi.org/10.3390/antibiotics3040617

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