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Disturbances of Modulating Molecules (FOXP3, CTLA-4/CD28/B7, and CD40/CD40L) mRNA Expressions in the Orbital Tissue from Patients with Severe Graves' Ophthalmopathy

Purpose. To evaluate the relationship between the expression of orbital tissue mRNA for FOXP3, CTLA-4/CD28/CD80/CD86, and CD40/CD40 and the severity of Graves' orbitopathy (GO). Material and Methods. Orbital tissue was obtained from 26 patients with GO, with mild (n = 6) or severe GO (n = 20),...

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Detalles Bibliográficos
Autores principales: Pawlowski, Przemyslaw, Wawrusiewicz-Kurylonek, Natalia, Eckstein, Anja, Reszec, Joanna, Luczynski, Wlodzimierz, Johnson, Kristian, Kretowski, Adam, Bakunowicz-Lazarczyk, Alina, Gorska, Maria, Szamatowicz, Jacek, Chyczewski, Lech, Mysliwiec, Janusz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4306377/
https://www.ncbi.nlm.nih.gov/pubmed/25653477
http://dx.doi.org/10.1155/2015/340934