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Elucidating Molecular Mass and Shape of a Neurotoxic Aβ Oligomer

[Image: see text] Alzheimer's disease (AD), the most prevalent type of dementia, has been associated with the accumulation of amyloid β oligomers (AβOs) in the central nervous system. AβOs vary widely in size, ranging from dimers to larger than 100 kDa. Evidence indicates that not all oligomers...

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Detalles Bibliográficos
Autores principales: Sebollela, Adriano, Mustata, Gina-Mirela, Luo, Kevin, Velasco, Pauline T., Viola, Kirsten L., Cline, Erika N., Shekhawat, Gajendra S., Wilcox, Kyle C., Dravid, Vinayak P., Klein, William L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2014
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4306476/
https://www.ncbi.nlm.nih.gov/pubmed/25343357
http://dx.doi.org/10.1021/cn500156r