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Tailoring the Implementation of New Biomarkers Based on Their Added Predictive Value in Subgroups of Individuals

BACKGROUND: The value of new biomarkers or imaging tests, when added to a prediction model, is currently evaluated using reclassification measures, such as the net reclassification improvement (NRI). However, these measures only provide an estimate of improved reclassification at population level. W...

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Detalles Bibliográficos
Autores principales: van Giessen, A., Moons, K. G. M., de Wit, G. A., Verschuren, W. M. M., Boer, J. M. A., Koffijberg, H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4306488/
https://www.ncbi.nlm.nih.gov/pubmed/25622035
http://dx.doi.org/10.1371/journal.pone.0114020