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Genes From a Translational Analysis Support a Multifactorial Nature of White Matter Hyperintensities

BACKGROUND AND PURPOSE—: White matter hyperintensities (WMH) of presumed vascular origin increase the risk of stroke and dementia. Despite strong WMH heritability, few gene associations have been identified. Relevant experimental models may be informative. METHODS—: We tested the associations betwee...

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Detalles Bibliográficos
Autores principales: Lopez, Lorna M., Hill, W. David, Harris, Sarah E., Valdes Hernandez, Maria, Munoz Maniega, Susana, Bastin, Mark E., Bailey, Emma, Smith, Colin, McBride, Martin, McClure, John, Graham, Delyth, Dominiczak, Anna, Yang, Qiong, Fornage, Myriam, Ikram, M. Arfan, Debette, Stephanie, Launer, Lenore, Bis, Joshua C., Schmidt, Reinhold, Seshadri, Sudha, Porteous, David J., Starr, John, Deary, Ian J., Wardlaw, Joanna M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4306534/
https://www.ncbi.nlm.nih.gov/pubmed/25586835
http://dx.doi.org/10.1161/STROKEAHA.114.007649