A surface plasmon resonance approach to monitor toxin interactions with an isolated voltage-gated sodium channel paddle motif

Animal toxins that inhibit voltage-gated sodium (Na(v)) channel fast inactivation can do so through an interaction with the S3b–S4 helix-turn-helix region, or paddle motif, located in the domain IV voltage sensor. Here, we used surface plasmon resonance (SPR), an optical approach that uses polarized...

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Detalles Bibliográficos
Autores principales: Martin-Eauclaire, Marie-France, Ferracci, Géraldine, Bosmans, Frank, Bougis, Pierre E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2015
Materias:
Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4306711/
https://www.ncbi.nlm.nih.gov/pubmed/25624450
http://dx.doi.org/10.1085/jgp.201411268

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4306711/
https://www.ncbi.nlm.nih.gov/pubmed/25624450
http://dx.doi.org/10.1085/jgp.201411268

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