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Herpes Simplex Virus 1 Us3 Deletion Mutant is Infective Despite Impaired Capsid Translocation to the Cytoplasm

Herpes simplex virus 1 (HSV-1) capsids are assembled in the nucleus bud at the inner nuclear membrane into the perinuclear space, acquiring envelope and tegument. In theory, these virions are de-enveloped by fusion of the envelope with the outer nuclear membrane and re-enveloped by Golgi membranes t...

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Detalles Bibliográficos
Autores principales: Wild, Peter, Leisinger, Sabine, de Oliveira, Anna Paula, Schraner, Elisabeth M., Kaech, Andres, Ackermann, Mathias, Tobler, Kurt
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4306828/
https://www.ncbi.nlm.nih.gov/pubmed/25588052
http://dx.doi.org/10.3390/v7010052