KSHV Reactivation and Novel Implications of Protein Isomerization on Lytic Switch Control

In Kaposi’s sarcoma-associated herpesvirus (KSHV) oncogenesis, both latency and reactivation are hypothesized to potentiate tumor growth. The KSHV Rta protein is the lytic switch for reactivation. Rta transactivates essential genes via interactions with cofactors such as the cellular RBP-Jk and Oct-...

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Detalles Bibliográficos
Autores principales: Guito, Jonathan, Lukac, David M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2015
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4306829/
https://www.ncbi.nlm.nih.gov/pubmed/25588053
http://dx.doi.org/10.3390/v7010072

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4306829/
https://www.ncbi.nlm.nih.gov/pubmed/25588053
http://dx.doi.org/10.3390/v7010072

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