NNK, a Tobacco-Specific Carcinogen, Inhibits the Expression of Lysyl Oxidase, a Tumor Suppressor

A tobacco-specific carcinogen, 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK), is believed to contribute to the cancer burden in cigarette smokers. To evaluate NNK effects on the expression of lysyl oxidase (LOX), a tumor suppressor, we examined this enzyme at various levels in NNK-treated rat...

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Detalles Bibliográficos
Autores principales: Cheng, Guang, Li, Jianmin, Zheng, Maoguen, Zhao, Yinzhi, Zhou, Jing, Li, Wande
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4306850/
https://www.ncbi.nlm.nih.gov/pubmed/25546273
http://dx.doi.org/10.3390/ijerph120100064

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4306850/
https://www.ncbi.nlm.nih.gov/pubmed/25546273
http://dx.doi.org/10.3390/ijerph120100064

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