Wnt5a promotes cancer cell invasion and proliferation by receptor-mediated endocytosis-dependent and -independent mechanisms, respectively

Wnt5a activates the Wnt/β-catenin-independent pathway and its overexpression is associated with tumor aggressiveness enhancing invasive activity. For this action, Wnt5a-induced receptor endocytosis with clathrin is required. Wnt5a expression was previously believed to be associated with cancer cell...

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Detalles Bibliográficos
Autores principales: Shojima, Kensaku, Sato, Akira, Hanaki, Hideaki, Tsujimoto, Ikuko, Nakamura, Masahiro, Hattori, Kazunari, Sato, Yuji, Dohi, Keiji, Hirata, Michinari, Yamamoto, Hideki, Kikuchi, Akira
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4306915/
https://www.ncbi.nlm.nih.gov/pubmed/25622531
http://dx.doi.org/10.1038/srep08042

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4306915/
https://www.ncbi.nlm.nih.gov/pubmed/25622531
http://dx.doi.org/10.1038/srep08042

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