Araguspongine C Induces Autophagic Death in Breast Cancer Cells through Suppression of c-Met and HER2 Receptor Tyrosine Kinase Signaling

Receptor tyrosine kinases are key regulators of cellular growth and proliferation. Dysregulations of receptor tyrosine kinases in cancer cells may promote tumorigenesis by multiple mechanisms including enhanced cell survival and inhibition of cell death. Araguspongines represent a group of macrocycl...

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Detalles Bibliográficos
Autores principales: Akl, Mohamed R., Ayoub, Nehad M., Ebrahim, Hassan Y., Mohyeldin, Mohamed M., Orabi, Khaled Y., Foudah, Ahmed I., El Sayed, Khalid A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4306938/
https://www.ncbi.nlm.nih.gov/pubmed/25580621
http://dx.doi.org/10.3390/md13010288

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4306938/
https://www.ncbi.nlm.nih.gov/pubmed/25580621
http://dx.doi.org/10.3390/md13010288

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