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Araguspongine C Induces Autophagic Death in Breast Cancer Cells through Suppression of c-Met and HER2 Receptor Tyrosine Kinase Signaling
Receptor tyrosine kinases are key regulators of cellular growth and proliferation. Dysregulations of receptor tyrosine kinases in cancer cells may promote tumorigenesis by multiple mechanisms including enhanced cell survival and inhibition of cell death. Araguspongines represent a group of macrocycl...
Autores principales: | Akl, Mohamed R., Ayoub, Nehad M., Ebrahim, Hassan Y., Mohyeldin, Mohamed M., Orabi, Khaled Y., Foudah, Ahmed I., El Sayed, Khalid A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4306938/ https://www.ncbi.nlm.nih.gov/pubmed/25580621 http://dx.doi.org/10.3390/md13010288 |
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