Ophiobolin O Isolated from Aspergillus ustus Induces G1 Arrest of MCF-7 Cells through Interaction with AKT/GSK3β/Cyclin D1 Signaling

Ophiobolin O is a member of ophiobolin family, which has been proved to be a potent anti-tumor drug candidate for human breast cancer. However, the anti-tumor effect and the mechanism of ophiobolin O remain unclear. In this study, we further verified ophiobolin O-induced G1 phase arrest in human bre...

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Detalles Bibliográficos
Autores principales: Lv, Cuiting, Qin, Wenxing, Zhu, Tonghan, Wei, Shanjian, Hong, Kui, Zhu, Weiming, Chen, Ruohua, Huang, Caiguo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4306945/
https://www.ncbi.nlm.nih.gov/pubmed/25603341
http://dx.doi.org/10.3390/md13010431

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4306945/
https://www.ncbi.nlm.nih.gov/pubmed/25603341
http://dx.doi.org/10.3390/md13010431

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