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Opposing regulation of endolysosomal pathways by long-acting nanoformulated antiretroviral therapy and HIV-1 in human macrophages

BACKGROUND: Long-acting nanoformulated antiretroviral therapy (nanoART) is designed to improve patient regimen adherence, reduce systemic drug toxicities, and facilitate clearance of human immunodeficiency virus type one (HIV-1) infection. While nanoART establishes drug depots within recycling and l...

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Detalles Bibliográficos
Autores principales: Araínga, Mariluz, Guo, Dongwei, Wiederin, Jayme, Ciborowski, Pawel, McMillan, JoEllyn, Gendelman, Howard E
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4307176/
https://www.ncbi.nlm.nih.gov/pubmed/25608975
http://dx.doi.org/10.1186/s12977-014-0133-5