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Opposing regulation of endolysosomal pathways by long-acting nanoformulated antiretroviral therapy and HIV-1 in human macrophages
BACKGROUND: Long-acting nanoformulated antiretroviral therapy (nanoART) is designed to improve patient regimen adherence, reduce systemic drug toxicities, and facilitate clearance of human immunodeficiency virus type one (HIV-1) infection. While nanoART establishes drug depots within recycling and l...
Autores principales: | Araínga, Mariluz, Guo, Dongwei, Wiederin, Jayme, Ciborowski, Pawel, McMillan, JoEllyn, Gendelman, Howard E |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4307176/ https://www.ncbi.nlm.nih.gov/pubmed/25608975 http://dx.doi.org/10.1186/s12977-014-0133-5 |
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