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Hypermethylation of the TGF-β target, ABCA1 is associated with poor prognosis in ovarian cancer patients
BACKGROUND: The dysregulation of transforming growth factor-β (TGF-β) signaling plays a crucial role in ovarian carcinogenesis and in maintaining cancer stem cell properties. Classified as a member of the ATP-binding cassette (ABC) family, ABCA1 was previously identified by methylated DNA immunoprec...
Autores principales: | , , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4307187/ https://www.ncbi.nlm.nih.gov/pubmed/25628764 http://dx.doi.org/10.1186/s13148-014-0036-2 |