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Quantification of Drug Transport Function across the Multiple Resistance-Associated Protein 2 (Mrp2) in Rat Livers

To understand the transport function of drugs across the canalicular membrane of hepatocytes, it would be important to measure concentrations in hepatocytes and bile. However, these concentration gradients are rarely provided. The aim of the study is then to measure these concentrations and define p...

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Detalles Bibliográficos
Autores principales: Bonnaventure, Pierre, Pastor, Catherine M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4307239/
https://www.ncbi.nlm.nih.gov/pubmed/25547484
http://dx.doi.org/10.3390/ijms16010135