Compartmentalization Role of A-Kinase Anchoring Proteins (AKAPs) in Mediating Protein Kinase A (PKA) Signaling and Cardiomyocyte Hypertrophy

The Beta-adrenergic receptors (β-ARs) stimulation enhances contractility through protein kinase-A (PKA) substrate phosphorylation. This PKA signaling is conferred in part by PKA binding to A-kinase anchoring proteins (AKAPs). AKAPs coordinate multi-protein signaling networks that are targeted to spe...

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Detalles Bibliográficos
Autores principales: Rababa’h, Abeer, Singh, Sonal, Suryavanshi, Santosh V., Altarabsheh, Salah Eldien, Deo, Salil V., McConnell, Bradley K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2014
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4307244/
https://www.ncbi.nlm.nih.gov/pubmed/25547489
http://dx.doi.org/10.3390/ijms16010218

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4307244/
https://www.ncbi.nlm.nih.gov/pubmed/25547489
http://dx.doi.org/10.3390/ijms16010218

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