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Compartmentalization Role of A-Kinase Anchoring Proteins (AKAPs) in Mediating Protein Kinase A (PKA) Signaling and Cardiomyocyte Hypertrophy

The Beta-adrenergic receptors (β-ARs) stimulation enhances contractility through protein kinase-A (PKA) substrate phosphorylation. This PKA signaling is conferred in part by PKA binding to A-kinase anchoring proteins (AKAPs). AKAPs coordinate multi-protein signaling networks that are targeted to spe...

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Detalles Bibliográficos
Autores principales:	Rababa’h, Abeer, Singh, Sonal, Suryavanshi, Santosh V., Altarabsheh, Salah Eldien, Deo, Salil V., McConnell, Bradley K.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2014
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4307244/ https://www.ncbi.nlm.nih.gov/pubmed/25547489 http://dx.doi.org/10.3390/ijms16010218

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