Cyclodextrin-Complexed Ocimum basilicum Leaves Essential Oil Increases Fos Protein Expression in the Central Nervous System and Produce an Antihyperalgesic Effect in Animal Models for Fibromyalgia

O. basilicum leaves produce essential oils (LEO) rich in monoterpenes. The short half-life and water insolubility are limitations for LEO medical uses. β-Cyclodextrin (β-CD) has been employed to improve the pharmacological properties of LEO. We assessed the antihyperalgesic profile of LEO, isolated...

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Detalles Bibliográficos
Autores principales: Nascimento, Simone S., Araújo, Adriano A. S., Brito, Renan G., Serafini, Mairim R., Menezes, Paula P., DeSantana, Josimari M., Lucca Júnior, Waldecy, Alves, Pericles B., Blank, Arie F., Oliveira, Rita C. M., Oliveira, Aldeidia P., Albuquerque-Júnior, Ricardo L. C., Almeida, Jackson R. G. S., Quintans-Júnior, Lucindo J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4307262/
https://www.ncbi.nlm.nih.gov/pubmed/25551603
http://dx.doi.org/10.3390/ijms16010547

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4307262/
https://www.ncbi.nlm.nih.gov/pubmed/25551603
http://dx.doi.org/10.3390/ijms16010547

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