Asymmetric Synthesis and Evaluation of Danshensu-Cysteine Conjugates as Novel Potential Anti-Apoptotic Drug Candidates

We have previously reported that the danshensu-cysteine conjugate N-((R)-3-benzylthio-1-methoxy-1-oxo-2-propanyl)-2-acetoxy-3-(3,4-diacetoxyphenyl) propanamide (DSC) is a potent anti-oxidative and anti-apoptotic agent. Herein, we further design and asymmetrically synthesize two diastereoisomers of D...

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Detalles Bibliográficos
Autores principales: Pan, Li-Long, Wang, Jie, Jia, Yao-Ling, Zheng, Hong-Ming, Wang, Yang, Zhu, Yi-Zhun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4307265/
https://www.ncbi.nlm.nih.gov/pubmed/25551606
http://dx.doi.org/10.3390/ijms16010628

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4307265/
https://www.ncbi.nlm.nih.gov/pubmed/25551606
http://dx.doi.org/10.3390/ijms16010628

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