Motor, Visual and Emotional Deficits in Mice after Closed-Head Mild Traumatic Brain Injury Are Alleviated by the Novel CB2 Inverse Agonist SMM-189

We have developed a focal blast model of closed-head mild traumatic brain injury (TBI) in mice. As true for individuals that have experienced mild TBI, mice subjected to 50–60 psi blast show motor, visual and emotional deficits, diffuse axonal injury and microglial activation, but no overt neuron lo...

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Detalles Bibliográficos
Autores principales: Reiner, Anton, Heldt, Scott A., Presley, Chaela S., Guley, Natalie H., Elberger, Andrea J., Deng, Yunping, D’Surney, Lauren, Rogers, Joshua T., Ferrell, Jessica, Bu, Wei, Del Mar, Nobel, Honig, Marcia G., Gurley, Steven N., Moore, Bob M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4307274/
https://www.ncbi.nlm.nih.gov/pubmed/25561230
http://dx.doi.org/10.3390/ijms16010758

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4307274/
https://www.ncbi.nlm.nih.gov/pubmed/25561230
http://dx.doi.org/10.3390/ijms16010758

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