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Potential Relationship between Inadequate Response to DNA Damage and Development of Myelodysplastic Syndrome

Hematopoietic stem cells (HSCs) are responsible for the continuous regeneration of all types of blood cells, including themselves. To ensure the functional and genomic integrity of blood tissue, a network of regulatory pathways tightly controls the proliferative status of HSCs. Nevertheless, normal...

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Detalles Bibliográficos
Autores principales: Zhou, Ting, Chen, Peishuai, Gu, Jian, Bishop, Alexander J. R., Scott, Linda M., Hasty, Paul, Rebel, Vivienne I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4307285/
https://www.ncbi.nlm.nih.gov/pubmed/25569081
http://dx.doi.org/10.3390/ijms16010966