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Novel Transcription Factor Variants through RNA-Sequencing: The Importance of Being “Alternative”

Alternative splicing is a pervasive mechanism of RNA maturation in higher eukaryotes, which increases proteomic diversity and biological complexity. It has a key regulatory role in several physiological and pathological states. The diffusion of Next Generation Sequencing, particularly of RNA-Sequenc...

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Detalles Bibliográficos
Autores principales: Scarpato, Margherita, Federico, Antonio, Ciccodicola, Alfredo, Costa, Valerio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4307332/
https://www.ncbi.nlm.nih.gov/pubmed/25590302
http://dx.doi.org/10.3390/ijms16011755