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Downregulation of EphA5 by promoter methylation in human prostate cancer

BACKGROUND: EphA5 is a member of the Eph/ephrin family and plays a critical role in the regulation of carcinogenesis. A significant reduction of EphA5 transcripts in high-grade prostate cancer tissue was shown using a transcriptomic analysis, compared to the low-grade prostate cancer tissue. As less...

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Detalles Bibliográficos
Autores principales: Li, Shibao, Zhu, Yingfeng, Ma, Chunguang, Qiu, Zhenhua, Zhang, Xinju, Kang, Zhihua, Wu, Zhiyuan, Wang, Hua, Xu, Xiao, Zhang, Hu, Ren, Guoqiang, Tang, Jianmin, Li, Xiangyu, Guan, Ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4307617/
https://www.ncbi.nlm.nih.gov/pubmed/25609195
http://dx.doi.org/10.1186/s12885-015-1025-3