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Effects of food and alcohol on the pharmacokinetics of an oral, extended-release formulation of hydrocodone in healthy volunteers
BACKGROUND: The purpose of this study was to evaluate the pharmacokinetics, bioavailability, and safety of oral extended-release hydrocodone (HC-ER) when administered with food or alcohol. METHODS: Two single-center, open-label, randomized, crossover studies were conducted in healthy volunteers. In...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove Medical Press
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4307648/ https://www.ncbi.nlm.nih.gov/pubmed/25653563 http://dx.doi.org/10.2147/CPAA.S70831 |