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Enzymatic cleavage of histone H3: a new consideration when measuring histone modifications in human samples
Histone modifications are increasingly being used as biomarkers of cancer prognosis and survival. However, we identified a cleavage product of histone H3 in human peripheral blood mononuclear cells, which interferes with measures of certain H3 modifications. Therefore, the potential for enzymatic cl...
Autores principales: | Howe, Caitlin G, Gamble, Mary V |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4307743/ https://www.ncbi.nlm.nih.gov/pubmed/25628766 http://dx.doi.org/10.1186/s13148-014-0041-5 |
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