Epigenetic Changes of EGFR play an important role in BRAF inhibitor Resistant Cutaneous Melanomas

BRAF mutations are frequent in cutaneous melanomas and BRAF inhibitors(BRAFi) have shown remarkable clinical efficacy in BRAF mutant melanoma patients. However, acquired drug resistance can occur rapidly and tumor(s) often progress thereafter. Various mechanisms of BRAFi resistance have recently bee...

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Detalles Bibliográficos
Autores principales: Wang, Jinhua, Huang, Sharon K., Marzese, Diego M., Hsu, Sandy C., Kawas, Neal P., Chong, Kelly K., Long, Georgina V., Menzies, Alexander M., Scolyer, Richard A., Izraely, Sivan, Sagi-Assif, Orit, Witz, Isaac P., Hoon, Dave S.B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4307785/
https://www.ncbi.nlm.nih.gov/pubmed/25243790
http://dx.doi.org/10.1038/jid.2014.418

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4307785/
https://www.ncbi.nlm.nih.gov/pubmed/25243790
http://dx.doi.org/10.1038/jid.2014.418

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