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Biophysical Characterization of Human Protamine-1 as a Responsive CEST MR Contrast Agent

[Image: see text] The protamines are a low-molecular-weight, arginine-rich family of nuclear proteins that protect chromosomal DNA in germ cells by packing it densely using electrostatic interactions. Human protamine-1 (hPRM1) has been developed as a magnetic resonance imaging (MRI) chemical exchang...

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Detalles Bibliográficos
Autores principales: Oskolkov, Nikita, Bar-Shir, Amnon, Chan, Kannie W.Y., Song, Xiaolei, van Zijl, Peter C.M., Bulte, Jeff W.M., Gilad, Assaf A., McMahon, Michael T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2014
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4307908/
https://www.ncbi.nlm.nih.gov/pubmed/25642384
http://dx.doi.org/10.1021/mz500681y