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A Role for RUNX3 in Inflammation-Induced Expression of IL23A in Gastric Epithelial Cells

RUNX3 functions as a tumor suppressor in the gastric epithelium, where its inactivation is frequently observed during carcinogenesis. We identified IL23A as a RUNX3 target gene in gastric epithelial cells. This was confirmed in a series of in vitro analyses in gastric epithelial cell lines. In eluci...

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Detalles Bibliográficos
Autores principales: Hor, Yit Teng, Voon, Dominic Chih-Cheng, Koo, Jason Kin Wai, Wang, Huajing, Lau, Wen Min, Ashktorab, Hassan, Chan, Shing Leng, Ito, Yoshiaki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4307917/
https://www.ncbi.nlm.nih.gov/pubmed/25008775
http://dx.doi.org/10.1016/j.celrep.2014.06.003