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Altered CD161(bright) CD8(+) Mucosal Associated Invariant T (MAIT)-Like Cell Dynamics and Increased Differentiation States among Juvenile Type 1 Diabetics

Type 1A diabetes (T1D) is believed to be caused by immune-mediated destruction of β-cells, but the immunological basis for T1D remains controversial. Microbial diversity promotes the maturation and activation of certain immune subsets, including CD161(bright) CD8(+) mucosal associated invariant T (M...

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Detalles Bibliográficos
Autores principales: Harms, Robert Z., Lorenzo, Kristina M., Corley, Kevin P., Cabrera, Monina S., Sarvetnick, Nora E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4307988/
https://www.ncbi.nlm.nih.gov/pubmed/25625430
http://dx.doi.org/10.1371/journal.pone.0117335