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Altered CD161(bright) CD8(+) Mucosal Associated Invariant T (MAIT)-Like Cell Dynamics and Increased Differentiation States among Juvenile Type 1 Diabetics
Type 1A diabetes (T1D) is believed to be caused by immune-mediated destruction of β-cells, but the immunological basis for T1D remains controversial. Microbial diversity promotes the maturation and activation of certain immune subsets, including CD161(bright) CD8(+) mucosal associated invariant T (M...
Autores principales: | Harms, Robert Z., Lorenzo, Kristina M., Corley, Kevin P., Cabrera, Monina S., Sarvetnick, Nora E. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4307988/ https://www.ncbi.nlm.nih.gov/pubmed/25625430 http://dx.doi.org/10.1371/journal.pone.0117335 |
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