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Overlapping mouse subcongenic strains successfully separate two linked body fat QTL on distal MMU 2

BACKGROUND: Mouse chromosome 2 is linked to growth and body fat phenotypes in many mouse crosses. With the goal to identify the underlying genes regulating growth and body fat on mouse chromosome 2, we developed five overlapping subcongenic strains that contained CAST/EiJ donor regions in a C57BL/6J...

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Detalles Bibliográficos
Autores principales: Gularte-Mérida, Rodrigo, Farber, Charles R, Verdugo, Ricardo A, Islas–Trejo, Alma, Famula, Thomas R, Warden, Craig H, Medrano, Juan F
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4308015/
https://www.ncbi.nlm.nih.gov/pubmed/25613955
http://dx.doi.org/10.1186/s12864-014-1191-8