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Amino acid substitutions in hemagglutinin of the 2009 pandemic influenza A(H1N1) viruses that might affect the viral antigenicity

BACKGROUND: During 2009 to 2012, Thailand had encountered 4 distinctive waves of the 2009 pandemic influenza A(H1N1) (H1N1pdm) outbreaks. Considering the RNA nature of the influenza viral genome, a mutation in hemagglutinin (HA) gene which led to change in antigenicity of the strains circulating dur...

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Detalles Bibliográficos
Autores principales: Kosoltanapiwat, Nathamon, Boonyuen, Usa, Pooruk, Phisanu, Iamsirithaworn, Sopon, Mungaomklang, Anek, Chokephaibulkit, Kulkanya, Auewarakul, Prasert, Puthavathana, Pilaipan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4308064/
https://www.ncbi.nlm.nih.gov/pubmed/25539651
http://dx.doi.org/10.1186/1756-0500-7-951