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A Computational Strategy to Select Optimized Protein Targets for Drug Development toward the Control of Cancer Diseases

In this report, we describe a strategy for the optimized selection of protein targets suitable for drug development against neoplastic diseases taking the particular case of breast cancer as an example. We combined human interactome and transcriptome data from malignant and control cell lines becaus...

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Detalles Bibliográficos
Autores principales: Carels, Nicolas, Tilli, Tatiana, Tuszynski, Jack A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4308075/
https://www.ncbi.nlm.nih.gov/pubmed/25625699
http://dx.doi.org/10.1371/journal.pone.0115054