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Inflammation and oxidative stress caused by nitric oxide synthase uncoupling might lead to left ventricular diastolic and systolic dysfunction in patients with hypertension

OBJECTIVE: To investigate the role of oxidative stress, inflammation, hypercoagulability and neuroendocrine activation in the transition of hypertensive heart disease to heart failure with preserved ejection fraction (HFPEF). METHODS: We performed echocardiography for 112 patients (≥ 60 years old) w...

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Detalles Bibliográficos
Autores principales: Szelényi, Zsuzsanna, Fazakas, Ádám, Szénási, Gábor, Kiss, Melinda, Tegze, Narcis, Fekete, Bertalan Csaba, Nagy, Eszter, Bodó, Imre, Nagy, Bálint, Molvarec, Attila, Patócs, Attila, Pepó, Lilla, Prohászka, Zoltán, Vereckei, András
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Science Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4308452/
https://www.ncbi.nlm.nih.gov/pubmed/25678898
http://dx.doi.org/10.11909/j.issn.1671-5411.2015.01.001