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Biological and clinical significance of PARP1 protein expression in breast cancer

Poly(ADP-ribose) polymerase-1 (PARP1) is a key facilitator of DNA repair. PARP inhibitors have gained recent attention as promising therapeutic agents for the treatment of solid tumours including breast cancer (BC). However, the biological and clinical significance of PARP1 expression in BC and its...

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Detalles Bibliográficos
Autores principales: Green, Andrew R., Caracappa, Daniela, Benhasouna, Ahmed A., Alshareeda, Alaa, Nolan, Christopher C., Macmillan, R. Douglas, Madhusudan, Srinivasan, Ellis, Ian O., Rakha, Emad A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4308637/
https://www.ncbi.nlm.nih.gov/pubmed/25528020
http://dx.doi.org/10.1007/s10549-014-3230-1