Placental Hofbauer cells assemble and sequester HIV-1 in tetraspanin-positive compartments that are accessible to broadly neutralizing antibodies

INTRODUCTION: Within monocyte-derived macrophages, HIV-1 accumulates in intracellular virus-containing compartments (VCCs) that are inaccessible to the external environment, which implicate these cells as latently infected HIV-1 reservoirs. During mother-to-child transmission of HIV-1, human placent...

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Detalles Bibliográficos
Autores principales: Johnson, Erica L, Chu, Hin, Byrareddy, Siddappa Nagadenahalli, Spearman, Paul, Chakraborty, Rana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International AIDS Society 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4308659/
https://www.ncbi.nlm.nih.gov/pubmed/25623930
http://dx.doi.org/10.7448/IAS.18.1.19385

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4308659/
https://www.ncbi.nlm.nih.gov/pubmed/25623930
http://dx.doi.org/10.7448/IAS.18.1.19385

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